Dr. Mehreen Lateef
Category:
April 24, 2017
| PERSONAL INFORMATION | ||
| Campus | Bahria University Health Sciences Campus |  |
| Department | Biochemistry | |
| Designation | Principal, Bahria University College of Allied Health Sciences | |
| Name | Dr. Mehreen Lateef | |
| principalbucahs.bumdc@bahria.edu.pk | ||
| Phone (Office Ext) | 021-35319491-9-1043 | |
| Research Area | Biochemistry, Medicinal chemistry, Clinical chemistry, Enzymology, Biotechnology | |
| Number of publication | 154 | |
| QUALIFICATION | |||
| Degree | Passing Year | Majors | University |
| Ph.D | 2013 | Biochemistry | University Of Karachi |
| Mphil | 2007 | Biochemistry | University Of Karachi |
| MSc | 2002 | Biochemistry | University Of Karachi |
| B.Sc (Hons) | 2001 | Biochemistry | University Of Karachi |
| TEACHING EXPERIENCE | |||
| Designation | From | To | Organization |
| Professor and Principal BUCAHS | Sep 2023 | Till to date | Bahria University Health Sciences Campus Karachi |
| Sr. Associate Professor | 2021 | 2023 | Bahria University Health Sciences Campus Karachi |
| Associate Professor | Sep 2019 | Sep 2021 | Bahria University Health Sciences Campus Karachi |
| Sr. Assistant Professor | Sep 2017 | Sep 2019 | Bahria University Health Sciences Campus Karachi |
| Assistant Professor & Head of Department of MultiDisciplinary Research lab | May 2015 | Sep 2019 | Bahria University Health Sciences Campus Karachi |
| Publications | |||
| 1. | Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug Entoban. Sadia Shakeel* Khan Usmanghani Somia Gul Zeeshan Ahmed Sheikh Syed Faisal Zaidi Mehreen Lateef African Journal of Pharmacy and Pharmacology, 29(40) :982-98 | ||
| 2. | Antimicrobial, antioxidant and butyrylcholinesterase inhibition activities of extracts and isolated compounds from Scadoxus pseudocaulus and semi-synthetic farrerol derivatives A.L. Ngankeu Pagninga, b, Jean-de-Dieu Tamokouc, M. Lateef Khan , M. Imran Alib, Abdul Hameedb, David Ngnokama, , , L. Azefack Tapondjoua, Jules-Roger Kuiatec, M. Shaiq Ali South African Journal of Botany 08/2015; DOI:10.1016/j | ||
| 3. | Cholinesterase activity as a potential biomarker for neurotoxicity induced by pesticides in vivo exposed Oreochromis niloticus (Nile tilapia): assessment tool for organophosphates and synthetic pyrethroids. Amin, Muhammad, Masarrat Yousuf, Mohammad Attaullah, Naveed Ahmad, Mohamad Nor Azra, Mehreen Lateef, Islam Dad Buneri et al. ” Environmental Technology (2022): 1-9. | ||
| 4. | Experimental and Theoretical investigations on (E)-3-(4-ethoxyphenyl)-1-(2-(trifluoromethyl) phenyl) prop‑2-en-1-one and (E)-3-(naphthalen-2-yl)-1-(2-(trifluoromethyl) phenyl) prop‑2-en-1-one: DNA binding, Urease inhibition and Promising NLO response. Rasool, Faiz, Ajaz Hussain, Khurshid Ayub, Muhammad Tariq, Khalid Mahmood, Sammer Yousuf, Muhammad Yar et al. ” Journal of Molecular Structure 1253 (2022): 132194. | ||
| 5. | Phytochemical constituents found in Physalis peruviana L. leaf extracts and their ability to inhibit alpha-glucosidase and scavenge DPPH free radicals in vitro.” Kasali, Félicien Mushagalusa, Muhammad Shaiq Ali, Jonans Tusiimire, Mehreen Lateef, Ruth Anyango Omole, Justin Ntokamunda Kadima, and Amon Ganafa Agaba. (2022). | ||
| 6. | One Pot Syntheses and Biological Screening of New Vanillic Acid Esters. Ali, Muhammad Shaiq, Jawad Ullah, Mehreen Lateef, Seerat Iqbal, and Sadia Zikr-Ur-Rehman.” Journal of the Chemical Society of Pakistan 44, no. 3 (2022). | ||
| 7. | 1, 3, 5-Thiadiazinane thione derivatives as significant urease inhibitors.” Arshad, Nuzhat, Mehreen Lateef, Jamshed Hashim, Aisha Anwar, Rima D. Alharthy, Hamza Azam, and Anwar Iqbal. Pakistan Journal of Pharmaceutical Sciences 35, no. 3 (Special) (2022): 911-917. | ||
| 8. | A New Flavone and Other Constituents from the Flowers and Fruits of Alstonia scholaris. Ali, Muhammad S., Aqsa Sultan, Mehreen Lateef, and Ayesha Ashfaq. “Chemistry of Natural Compounds 58, no. 2 (2022): 233-236. | ||
| 9. | Atricephenols A and B, two phenolic compounds from Indigofera atriceps Hook. f.(Fabaceae). Mouafon, Iliassou Lah, Bel Youssouf Gbetnkom Mountessou, Mehreen Lateef, Joseph Tchamgoue, Muhammad Shaiq Ali, Jean Claude Tchouankeu, Ivan Robert Green, Bonaventure Tchaleu Ngadjui, and Simeon Fogue Kouam.” Natural Product Research (2022): 1-8. | ||
| 10. | Phytochemical constituents found in Physalis peruviana L. leaf extracts and their ability to inhibit alpha-glucosidase and scavenge DPPH free radicals in vitro.” Kasali, Félicien Mushagalusa, Muhammad Shaiq Ali, Jonans Tusiimire, Mehreen Lateef, Ruth Anyango Omole, Justin Ntokamunda Kadima, and Amon Ganafa Agaba. (2022). | ||
| 11. | Phytochemical Screening and Biological Evaluation of Young Stems of Alstonia scholaris. Ali, Muhammad Shaiq, Ayesha Ashfaq, Mehreen Lateef, Aqsa Sultan, Sadia Zikr-ur-Rehman, and Zafar Saeed Saify.” Journal of the Chemical Society of Pakistan 43, no. 5 (2021). | ||
| 12. | In-vitro dose response effect of bergenin on platelet aggregation by inhibiting inducers (collagen and ADP) and lipoxygenase.” Hussain, Muzammil, Rehana Perveen, Mehreen Lateef, Zuneera Akram, Iqbal Azhar, and Saima Saleem. (2021). | ||
| 13. | Junejo, Shizma, Shazia Shakoor, Zille Huma Mustehsan, Mehreen Lateef, Hamza Iftikhar, and Sarah Rabbani. “Use of nutritional supplements amongst individuals exercising at gymnasiums.” PROGRESS IN NUTRITION 23, no. 3 (2021). | ||
| 14. | Facile synthesis, DNA binding, Urease inhibition, anti-oxidant, molecular docking and DFT studies of 3-(3-Bromo-phenyl)-1-(2-trifluoromethyl-phenyl)-propenone and 3-(3-Bromo-5 chloro-phenyl)-1-(2-trifluoromethyl-phenyl)-propenone.” Rasool, Faiz, Muhammad Khalid, Muhammad Yar, Khurshid Ayub, Muhammad Tariq, Ajaz Hussain, Mehreen Lateef, Muhammad Kashif, and Sana Iqbal. Journal of Molecular Liquids 336 (2021): 116302. | ||
| 15. | A new dammarane type triterpene glucoside from the aerial parts of Gouania longipetala (Rhamnaceae).” Désiré, Soh, Nkwengoua Ernestine, Tchebemou Bakang Bruno, Sidjui Sidjui Lazare, Dzo Defokou Ulrich, Mehreen Lateef, Bernd Schneider, Muhammad Shaiq Ali, and Nyassé Barthélemy. Natural product research 35, no. 19 (2021): 3192-3203. | ||
| 16. | Steroidal Saponins from Solanum torvum Swartz Collected in Dibombari, Cameroon. Lacmago AB, Songue JL, Fouda AA, Ekon JP, Lateef M, Ali MS, Wansi JD, Sewald N, Happi EN, Waffo AF. South Asian Research Journal of Natural Products. 2021 Feb 19:16-23. | ||
| 17. | Impact of Vitamin C as an Adjuvant Agent on Glycemic Indices in Type 2 Diabetes Mellitus: Randomized Clinical Trial. Ishrat S, Hoor T, Jaffri MS, Junejo S, Lateef M. Journal of Bahria University Medical and Dental College. 2021 Jul 1;11(3):102-6. | ||
| 18. | Zenkeramide: a new iso-benzofuranone propanamide and urease inhibitory constituents of Celtis zenkeri Engl stem bark (Ulmaceae). Okpala EO, Onocha PA, Ali MS, Ur-Rehmen SZ, Lateef M. Natural Product Research. 2021 Jul 12:1-6. | ||
| 19. | Crotoliganfuran, a new clerodane-type furano-diterpenoid from Croton oligandrus Pierre ex Hutch. Yannick Stephane, Fongang Fotsing, Amadou Dawe, Awantu Angelbert Fusi, Bankeu Kezetas Jean Jules, Kagho Kenou Donald Ulrich, Mehreen Lateef, Lenta Ndjakou Bruno, Muhammad Shaiq Ali, and Silvère Augustin Ngouela. “Natural product research 35, no. 1 (2021): 63-71. | ||
| 20. | 2‐Mercapto Benzoxazole Derivatives as Novel Leads: Urease Inhibition, In Vitro and In Silico Studies. Balogun MM, Shamim S, Khan KM, Salar U, Oladosu IA, Lateef M, Wadood A, Taha M, Moronkola DO, Rehman AU, Rahim F. ChemistrySelect. 2021 Sep 7;6(33):8490-8. | ||
| 21. | Emmanuel Ngeufa Happi, Moses Kiprotich Langat et al. “Bioactive constituents from Manilkara obovata (Sabine & G. Don) JH Hemsl.” Akosung, Emmanuel, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Natural product research (2020): 1-10. | ||
| 22. | Evaluation of C-reactive protein in breast cancer by enzyme linked immunoassay technique.” Usmani, Ambreen, and Mehreen Lateef. JPMA. The Journal of the Pakistan Medical Association 71, no. 1 (A) (2021): 424-428. | ||
| 23. | N-Aryl-3, 4-dihydroisoquinoline Carbothioamide Analogues as Potential Urease Inhibitors.” Ali, Fayaz, Shahbaz Shamim, Mehreen Lateef, Khalid Mohammed Khan, Muhammad Taha, Uzma Salar, Abdul Wadood, Ashfaq Ur Rehman, Noor Ul Ain Nawaz, and Shahnaz Perveen. ACS Omega (2021). | ||
| 24. | Biological activities of the methanolic extracts and compounds from leaves and twigs of Diospyros zenkeri (Gürke) F. White (Ebenaceae) Hermann Feumo Feusso; Jean de dieu Dongmo; Carine Mvot Akak; Mehreen Lateef; Ayaz Ahmed; Anatole Guy Blaise Azebaze; Alain François Kamdem Waffo; Muhammad Shaiq Ali; Juliette Catherine Vardamides. South Asian Research Journal of Natural Products, 16-23 Volume 3, Issue 2 , Spring 2019, , Pages 117-122. |
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| 25. | Intortins A–C: new isoflavonoids from the roots of Desmodiumintortum (Fabaceae). ADK Mboussaah, M Lateef, SPC Fodouop, AE Nkengfack, BN Lenta, Chemical Data Collections 33, 100678. | ||
| 26. | Chemical constituents of the medicinal plant Indigofera spicata Forsk (Fabaceae) and their chemophenetic significance. IL Mouafon, GLM Tiani, BYG Mountessou,M Lateef. Biochemical Systematics and Ecology 95, 104230 | ||
| 27. | A new cerebroside and bioactive compounds from Celtis adolphi-friderici Engl.(Cannabaceae) KJD Jumeta, DUK Kagho, JET Ateba, YSF Fotsing, JJK Bankeu, M. lateef Biochemical Systematics and Ecology 94, 104201. | ||
| 28. | KJD Jumeta, DUK Kagho, JET Ateba, YSF Fotsing, JJK Bankeu, M. Lateef.Biochemical Systematics and Ecology 94, 104201M Lateef, MS Ali, IR Green,Biochemical Systematics and Ecology 95, 104230 | ||
| 29. | Oligandrin, a New Ent-Pimarane Type Diterpenoid and Other Bioactive Constituents from the Leaves of Croton oligandrus. YSF Fongang, AF Awantu, JJK Bankeu, M Lateef, BN Lenta, MS Ali, .Chemistry of Natural Compounds 57 (1), 94-100 | ||
| 30. | Smoking amid Covid-19; a jeopardy calling attention. S Junejo, KM Memon, M Lateef – Rawal Medical Journal, 2020 | ||
| 31. | Muricazine, a new hydrazine derivative from Ranunculus muricatus L. with antioxidant, lipoxygenase and urease inhibitory activities, Naila Raziq, Muhammad Saeed, Muhammad Shaiq Ali, Muhammad Shahid, Mehreen Lateef & Salman Zafar (2020) Natural Product Research, DOI: 10.1080/14786419.2020.1855169 | ||
| 32. | New bioactive monoterpene indole alkaloid from Rinorea yaundensis Engl., Bushra Khatoon, Sadia Zikr Ur Rehman, Sammar Yousuf, Mehreen Lateef, Martial Flora Adjapmoh Essombo, Alain Francois Kamdem Waffo & Muhammad Shaiq Ali (2020) Natural Product Research, DOI: 10.1080/14786419.2020.1855160 | ||
| 33. | Secondary Metabolites From The Leaves And Defoliated Twigs Of Alstonia scholaris M. S. Ali, E. A. Ali, H. Kausar, S. Zikr-Ur-Rehman, Z. S. Saify, and M. Latif Chemistry of Natural Compounds, 56, No. 6, November, (2020) | ||
| 34. | Muriolide, a novel antioxidant lactone from Ranunculus muricatus” Naila Raziq, Muhammad Saeed, Muhammad Shaiq Ali, Mehreen Lateef, Muhammad Shahid, Shehla Akbar, and Salman Zafar. Natural Product Research (2020): 1-7. | ||
| 35. | Ceramides and other bioactive compounds from Celtis tessmannii Rendle” Kagho, Donald UK, Yannick SF Fongang, Angelbert F. Awantu, Jean JK Bankeu, Rufin MK Toghueo, Augustin S. Ngouela, Norbert Sewald, Bruno N. Lenta, Lateef Mehreen, and Muhammad S. Ali. Chemical Data Collections (2020): 100483. | ||
| 36. | 4-Oxycoumarinyl linked acetohydrazide Schiff bases as potent urease inhibitors.” al-Rashida, Mariya, Irfan Ali, Basharat Ali, Muhammad Taha, and Shahnaz Perveen. Bioorganic Chemistry 105 (2020): 104365. | ||
| 37. | Native wild plants in Karachi, Pakistan: Rich source of antioxidant raw material.” Lateef, Mehreen, Sadia Farheen, Beena Naqvi, Lubna Iqbal, and Kauser Siddiqui. Pakistan Journal of Pharmaceutical Sciences 33, no. 3 (2020). | ||
| 38. | The chemistry and biological activities of Citrus clementina Hort. Ex Tanaka (Rutaceae), a vegetatively propagated species” Samuel Bissim, Magloire, Sidonie Beatrice Kenmogne, Jules Songue Lobe, Albert Fouda Atangana, Achile Nouga Bissoue, Moses K. Langat. Natural Product Research (2020): 1-4. | ||
| 39. | Serum Alanine Aminotransferase Levels in Hepatitis-C Patients of District Rahim Yar Khan, Pakistan.” Mohammad Ali Malik, Mohammad Abdul Rehman, Mehreen Lateef, and Shafaq Mahmood. Science Letters (2020): 23-27. | ||
| 40. | Bioactive constituents from Manilkara obovata (Sabine & G. Don) JH Hemsl.” Emmanuel Akosung, Sidonie Beactrice Kenmogne, Jules Lobe Songue, Jean Pierre Longue Ekon, Mehreen Lateef, Emmanuel Ngeufa Happi, Moses Kiprotich Langat. Natural product research (2020): 1-10. | ||
| 41. | Biological activities of the methanolic extracts and compounds from leaves and twigs of” Feumo Feusso, Hermann, Carine Mvot Akak, Mehreen Lateef, Ayaz Ahmed, Anatole Guy Blaise Azebaze, Alain François Kamdem Waffo, Muhammad Shaiq Ali, and Juliette Catherine Vardamides. Trends in Phytochemical Research 3, 2019, 117-122. | ||
| 42. | A new dammarane type triterpene glucoside from the aerial parts of Gouania longipetala (Rhamnaceae).” Soh Désiré, Nkwengoua Ernestine, Tchebemou Bakang Bruno, Sidjui Sidjui Lazare, Dzo Defokou Ulrich, Mehreen Lateef, Bernd Schneider, Muhammad Shaiq Ali, and Nyassé Barthélemy. Natural Product Research (2019): 1-12. | ||
| 43. | Transmission routes of hepatitis c virus infection In Rahim yar khan: hospital based study” M. Ali Malik, M.A. Rehman Nadia Usman, Mehreen Lateef, Shizma Junejo. Journal of BioSciences (2019): 418-424. | ||
| 44. | 8‐Hydroxyquinoline‐Methionine Mixed Ligands Metal Complexes: Preparation and Their Antioxidant Activity” Noshab Qamar, Hira Sultan, Khalid Mohammed Khan, Rafia Azmat, Raheela Naz, Abdul Hameed, Mehreen Lateef. Chemistry Select (2019): 2967-3273 | ||
| 45. | Heterochelates of metals as an effective anti – Urease agents couple with their docking studies” Noshab Qamar, Hira Sultan, Ahmad Raheel, Maria Ashfaq, Rafia Azmat, Raheela Naz, Mehreen Lateef, Khalid Mohammed Khan, Tanzila Arshad. Pakistan journal of pharmaceutical sciences (2019). | ||
| 46. | Enzyme inhibition, Antioxidant and Insecticidal activities of flavonoids and fixed oil from Albizia zygia (J. F.Macbr)” Oloyede, Oloyede, Ganiyat, Mohammed Alli, and Mehreen Lateef. In abstracts of papers of the american chemical society (2019). | ||
| 47. | Biological Screening Of Synthesized Oxalamide Derivatives For Antioxidant And Anticancer Properties.” Fazal-ur-Rehman, Saba, Agha Arslan Wasim, Qurratulain, M. Khan, Mehreen, Lateef and L. Iqbal. (2019) INT. J. BIOL. BIOTECH., 16 (3): 593-600, 2019. | ||
| 48. | Bioactive acridone alkaloids and their derivatives from Citrus aurantium (Rutaceae)” Samuel Bissim, Sidonie Béatrice Kenmognea Alain Tadjong Tchoa, Mehreen Lateefd, Ayaz Ahmede, Emmanuel Ngeufa Happia, Jean Duplex Wansia Muhammad Shaiq Alib, Alain François Kamdem Waffoa. Phytochemistry Letters (2019):148–153. | ||
| 49. | Metal based biologically active compounds: synthesis, spectral, and antioxidant studies of transition metal complexes with hydrazone derivatives” Muhammad Asad Khan Tanoli, Zahid Khan, Tooba Kamal, Zaahida T. Mehreen Lateef, Mohsin Ali. Pakistan Journal of Pharmaceutical Sciences (2019). | ||
| 50. | Biological activities of the methanolic extracts and compounds from leaves and twigs of Diospyros zenkeri (Gürke) F. White (Ebenaceae)” Hermann Marius Feumo Feusso, Jean de dieu Dongmo, Carine Mvot Akak, Mehreen Lateef, Ayaz Ahmed, Anatole Guy Blaise Azebaze, Alain François Kamdem Waffo, Muhammad Shaiq Ali, Juliette Catherine Vardamides, Trends Phytochemical Research (2019): 117-122. | ||
| 51. | Chemistry, Alpha-glucosidase and Radical Scavenging Properties of Uranyl(VI) Hydrazide Complexes” Parveen Akhter, Uzma Ashiq, Rifat A. Jamal, Zara Shaikh, Mohammad Mahroof-Tahir, Mehreen Lateef, Rooma Badar. Medicinal Chemistry (2019): 923-936. | ||
| 52. | Natural products from the medicinal plant Duguetia staudtii (Annonaceae)” Ngouonpe, Alain W, Mbobda Alexis Sylvain W, Happi Gervais M, Mbiantcha Marius, Tatuedom Ostend K, Ali Muhammad S, Lateef, Mehreen, Tchouankeu Jean Claude, Kouam Siméon F. Biochemical Systematics And Ecology (2019): 22-25. | ||
| 53. | Oligoamide, a new lactam from the leaves of Angylocalyx oligophyllusweka” Brussine Nadège Wakeu, Jouda Jean-Bosco, Melacheu Gertrude Foudjo, Sidjui Lazare Sidjui, Mkounga, Pierre Lateef Mehreen, Ali Muhammad Shaiq, Wandji Jean, Mbazoa Céline Djama. Natural Product Research, (2019): 2011-2015. | ||
| 54. | Synthesis, lipoxygenase inhibition activity and molecular docking of oxamide derivative” Fazal-ur-Rehman, Saba, Agha Arslan Wasim, Sadaf Iqbal, Maria Aqeel Khan, Mehreen Lateef, and Lubna Iqbal. Pakistan journal of pharmaceutical sciences (2019):1253-1259. | ||
| 55. | Viridone, A New Butyrylcholinesterase Inhibitory Phenolic Ester From Leaves of Ocimum viride” Almas Hashmi, Muhammad Shaiq Ali, Mehreen Latif, Zeeshan Ahmed, and Joseph Ngoupayo. Chemistry of Natural Compounds, (2018): 665-668. | ||
| 56. | Hamdullah Khadim Sheikh, Merrick Pierson-Smela, Tanzila Arshad, Mehdi Hassan Kazmi, Sadia Farheen, Mehreen Lateef Antioxidant Activity Of Azo Glycol Derivative And Their Cu Coordinates INT. J. BIOL. BIOTECH., 15 (3): 483-491, 2018. | ||
| 57. | Classical and Variant Approaches to Synthesis of N-Mannich Bases of Phenyl Hydroxyl Ketones, Their Characterization, Urease Inhibition and Antioxidant Activities” Oloyede, Ganiyat, Shaiq Ali, Mehreen Lateef, Gabriel Anyaele, and Adeniyi Mayowa. In abstracts of papers of the american chemical society (2018). | ||
| 58. | Immunomodulatory activities of extracts of Caesalpinia pulcherrima” Fouzia Khan, Nida Dastagir, Mehreen Lateef, Muhammad Yousuf, Zulfiqar Ali Mirani, Ahmed Mesaik, Shaheen Faizi, and Shahana Urooj Kazmi. Journal of Herbs, Spices & Medicinal Plants, (2018): 245-256. | ||
| 59. | Bioactivity and conformational study of novel glycol Azo Derivatives” Hamdullah Khadim Sheikh, Tanzila Arshad, Mehdi Hassan Kazmi, Sadia Ferheen, Tehmina Sohail and Mehreen Lateef. International Journal of Biology and Biotechnology, (2018): 185-191. | ||
| 60. | In silico and BSA binding study of some new biological analogs of 1,2,4-triazole pendant with azinane through microwave and conventional synthesis” Naeem Akhtar Virk, Aziz-ur-Rehman, Muhammad Athar Abbasi, Sabahat Zahra Siddiqui, Asma Ashraf, Mehreen Lateef, Hira Javed, Javed Iqbal , Hira Khalid and Shafi Ullah Khan. Pakistan journal of Pharmaceutical Sciences, (2018): 2645-2645. | ||
| 61. | Kostchyienones A and B, new antiplasmodial and cytotoxicity of limonoids from the roots of Pseudocedrela kotschyi (Schweinf.) Harms, Sidjui, Lazare S., Yves OD Nganso, Rufin MK Toghueo, Brussine NK Wakeu, Joel T. Dameue, Pierre Mkounga, Achyut Adhikari, Mehreen Lateef, Gabriel N. Folefoc, and Muhammad S. Ali. Zeitschrift fur Naturforschung. C, Journal of Biosciences, (2018): 153-160. | ||
| 62. | New bioactive triaryl triglyceride esters: Synthesis, characterization and biological activities” Tanzila Arshad Hamdullah Khadim Sheikh, Mehdi Hassan Kazmi, Sadia Farheen,Tehmina Sohail and Mehreen Lateef. Bangladesh Journal of Pharmacology, (2018): 302-308. | ||
| 63. | Flavonoids and triterpenes from Combretum fragrans with anti-inflammatory, antioxidant and antidiabetic potential” Dawé, Amadou, Marius Mbiantcha, Fawai Yakai, Almas Jabeen, Muhammad Shaiq Ali, Mehreen Lateef, and Bonaventure Tchaleu Ngadjui. Zeitschrift für Naturforschung C (2018): 211-219. | ||
| 64. | Facile one-pot syntheses of new C-28 esters of oleanolic acid and studies on their antiproliferative effect on T cells” Ali, Muhammad S., Ghafoor Ahmed, Muhammad A. Mesaik, Muhammad R. Shah, Mehreen Lateef, and Muhammad I. Ali. .” Zeitschrift für Naturforschung C” (2018), 417-421. | ||
| 65. | Dioclins A and B, new antioxidant flavonoids from Dioclea reflexa” Abdulkabir OladeleOladimeji, Ibrahim Adebayo Oladosu,Muhammad Shaiq Ali and Mehreen Lateef. Natrual Product Research, (2018): 2017-2024. | ||
| 66. | Evaluation of some biological activities of Abelia triflora R Br (Caprifoliaceae) constituents” Fawzy, Ghada A., Shagufta Perveen, Areej M. Al-Taweel, Raha S. Orfali, Lubna Iqbal, Mehreen Lateef, Rasool B. Tareen, and Shabana I. Khan. Tropical Journal of Pharmaceutical (2017): 319-325. | ||
| 67. | A new glycosidic antioxidant from Ranunculus muricatus L. (Ranunculaceae) exhibited lipoxygenasae and xanthine oxidase inhibition properties” Naila Raziq, Muhammad Saeed, Muhammad Shaiq Ali, Salman Zafar, Muhammad Shahid & Mehreen Lateef. Natural Product Research (GNPL), (2017): 1251-125. | ||
| 68. | Vanadium(V) complexes with hydrazides and their spectroscopic and biological properties” Sadaf Sultan, Uzma Ashiq, Rifat Ara Jamal, Mohammad Mahroof-Tahir, Zara Shaikh, Bushra Shamshad, Mehreen Lateef, Lubna Iqbal. Biometals, (2017):873–891. | ||
| 69. | Sessilifol A and B, Urease Inhibitory Pimarane-type Diterpenes from Hymenocrater sessilifolius” Sadia Khana, Muhammad Shaiq Ali, Zeeshan Ahmed, Mehreen Lateef, Sammer Yousufa , Viqar Uddin Ahmada, Itrat Fatimaa and Rasool Bakhsh Tareend. Natrual Product Communications (2017):1831–1833. | ||
| 70. | Characterization of bioactive compounds from Ficus vallis-choudae Delile (Moraceae)” Jean Jules Kezetas Bankeu ,Amadou Dawé , Marius Mbiantcha , Guy Raymond Tchouya Feuya , Iftikhar Ali , Marthe Aimée Tchuente Tchuenmogne, Lateef Mehreen , Bruno Ndjakou Lenta, ,Muhammad Shaiq Ali2 and Augustin Silvère Ngouela. Trends in Phytochemical Research, (2017): 235-242. | ||
| 71. | New anthrarobin acyl derivatives as butyrylcholinesterase inhibitors: synthesis, in vitro and in silico studies” Mehreen Lateef, Abid Azhar, Bina S. Siddiqui , Shamshad Zarina , Nizam uddin , Muhammad F. Anwar, Kauser Siddiqui, Kaniz F. Azhar , Lubna Iqba , Rashad Mehmood, Shagufta Perveen. Heliyon (2017): 3-7. | ||
| 72. | Antioxidant and Enzyme Inhibitory Constituents from Dactyladenia floribunda and Chemicals Transformations of Hennadiol” Adjapmoh Essombo Martial Flora, Mbaze Meva’a Luc Leonard, Wansi Jean Duplex, Muhammad Shaiq Ali, Kamdem Waffo Alain François, Takou Dieudonné Martial, Mehreen Lateef. Natural Products Chemistry and Research (2017): 2. | ||
| 73. | Piptadenin, a Novel 3, 4-secooleanane Triterpene and Piptadenamide, a New Ceramide from the stem bark of Piptadeniastrum africana (Hook. f.) Brenan” Mbiantcha, Yannick Fongang, William Yosseu Nana, Fawai Yakai, Gilbert Ateufack, Muhammad Ali Shaiq, Iqbal Lubna, Mehreen Lateef, Bonaventure Tchaleu Ngadjui. Chemistry & biodiversity (2017): e1600215 | ||
| 74. | hypochrysea (Chrysobalanaceae)” Martial F E Adjapmoh, Flavien A A Toze, Jules L Songue, Moses K Langat, Gilbert D W F Kapche, Abdul Hameed, Mehreen Lateef, Muhammad A Shaiq, Luc M Mbaze, Jean D Wansi, Alain F W Kamdem. Natural product communications (2016): 615-620. | ||
| 75. | 1,2,3,4,6-Pentakis[-O-(3,4,5-trihydroxybenzoyl)]-α,β-D-glucopyranose(PGG) analogs: design, synthesis, anti-tumor and anti-oxidant activities” Qurat-Ul-Ain Shaikh, Meiting Yang, Khadim Hussain Memon, Mehreen Lateef, Du Na, Shengbiao Wan, Deslandes Eric, Lijuan Zhang, Tao Jiang. Carbohydrate Research, (2016): 72-81. | ||
| 76. | Antimicrobial, antioxidant and butyrylcholinesterase inhibition activities of extracts and isolated compounds from Scadoxus pseudocaulus and semi-synthetic farrerol derivatives Pagning, AL Ngankeu, M. Lateef Khan, M. Imran Ali, Abdul Hameed, David Ngnokam, L. Azefack Tapondjou, Jules-Roger Kuiate, and M. Shaiq Ali. South African Journal of Botany, (2016): 166–174. | ||
| 77. | New triterpene and new flavone glucoside from Rhynchospora corymbosa (Cyperaceae) with their antimicrobial, tyrosinase and butyrylcholinesterase inhibitory activities” Annie Laure Ngankeu Pagning, Jean-de-Dieu Tamokouc, Mehreen Lateefd, Léon Azefack Tapondjoua, Jules-Roger Kuiatec, David Ngnokama, Muhammad Shaiq Alib. Phytochemistry Letters, (2016): 121–128. | ||
| 78. | Evaluation of in vitro antioxidant, reducing, lipoxygenase and ACE inhibition activity of polyherbal drug linkus” Hina Rehman, Zeeshan Ahmed Shaikh, Safila Naveed, Mahreen Latif. African Journal of Pharmacy and Pharmacology (2016): 945-95. | ||
| 79. | Evaluation of in vitro antioxidant capacity and reducing potential of polyherbal drug Entoban” Sadia Shakeel Khan, Usmanghani Somia, Gul Zeeshan Ahmed, Sheikh Syed, Faisal Zaidi, Mehreen Lateef. African Journal of Pharmacy and Pharmacology, (2015): 982-987. | ||
| 80. | Cashmins A and B, Potent Antioxidant Coumarins from Sorbus cashmiriana” Sadia Khan, Itrat Fatima, Mehdi Hussain Kazmi, Abdul Malik, Nighat Afza, Lubna Iqbal, Mehreen Latif. Chemistry of Natural Compounds, (2015) 626-629. | ||
| 81. | Synthesis, Characterization, In-Vitro Antimicrobial and Antioxidant Activities of Co+2, Ni+2, Cu+2 and Zn+2 Complexes of 3-(2-(2-hydroxy methoxybenzylidene) hydrazonoindolin-2-one” Zahid Khan, Zahida T. Maqsood, Muhammad Asad K. Tanoli, Khalid M. Khan, Lubna Iqbal and Mehreen Lateef. Journal of Basic & Applied Sciences, (2015): 125-130. | ||
| 82. | Antioxidant potential of anthrarobin (1,2,10- trihydroxy anthracene) and its acyl derivatives” Mehreen Lateef, Nizammuddin, Sobiya Pervaiz, Bina S. Sidduiqui,Saeeda Bano, Abid Azhar, Kanwal Abbassi, Kauser Sidduiqui, Kaniz Fizza Azhar. Journal of Chemical Society of Pakistan, (2015), 1015-1019. | ||
| 83. | Flavonoids and other bioactive constituents from Ficus thonningii Blume (Morceae)” Yannick S.F. Fongang, Jean J.K. Bankeu, Muhammad S. Ali, Angelbert F. Awantu , Ahmed Zeeshan , Clement N. Assob, Lateef Mehreen, Bruno N. Lenta , Silvere A. Ngouela, Etienne Tsamo. Phytochemistry Letters, (2015) 139-145. | ||
| 84. | Unsymmetrical 1,3-disubstituted urea derivatives as α-chymotrypsin inhibitors” Shahnaz Perveen, Sana Mustafa, Mehreen Latif, Lubna Iqbal, Tanzil H. Usmani, Khalid Mohammed Khan, Wolfgang Voelter. Medicinal Chemistry Research, (2014): 1554-8120. | ||
| 85. | Role of protein denaturing agents and EDTA on α-amylase activity from Bacillus subtilis” Saeeda Bano, Mehreen Lateef, Samina Iqbal, Beena Naqvi and Lubna Iqbal. International Journal of Pharmaceutical, Chemical and Biological Sciences, (2014) 411-415. | ||
| 86. | Copper (II) Complexes of Bishydrazone Derivatives: Synthesis, Characterization and Urease Inhibition Studies” Muhammad Asad Khan Tanoli, Zahid Khan, Zaahida T. Maqsood, Lubna Iqbal, Mehreen Lateef, Zahid Hussain. Middle-East Journal of Scientific Research, (2014): 698-703. | ||
| 87. | Urease inhibitory isoflavonoids from different parts of Calopogonium mucunoides (Fabaceae), Brigitte” Ndemangou, Valerie Tedjon Sielinou, Juliette Catherine Vardamides, Muhammad Shaiq Ali, Mehreen Lateef, Lubna Iqbal, Nigaht Afza, Augustin Ephrem Nkengfack, Journal of Enzyme Inhibition and Medicinal Chemistry, (2013): 1156-1161. | ||
| 88. | Synthesis, Spectroscopic characterization and pharmacological evaluation of oxazolone derivatives” Ghulam Fareed, Uzma Rasheed Mughal, Mehboob Ali Kulhoro, Lubna Iqbal, Mehreen Lateef, Journal of the Serbian Chemical Society, (2013): 1127-31. | ||
| 89. | Structure activity relationship: Antioxidant potential of some novel Schiff bases containing benzophenone moiety” Ghulam Fareed, Muhammad Ali Virsiani, Nighat Afza, Nazia Fareed, Lubna Iqbal and Mehreen Lateef, International Journal of Current Pharmaceutical Research, (2013): 61-64. | ||
| 90. | Phytochemical screening of total phenolic contents and and biological evaluation of aerial parts of Nepeta praciervisa” G Fareed, N. Afza, A. Malik, M.A. Versiani, M. Lateef, N. Fareed, U.R Mughal, R.B. Tareen and L. Iqbal, Journal of Chemical Society of Pakistan, (2013):1364-1368. | ||
| 91. | A Potent Urease Inhibitor: 2-{[(2-{[€-(Hydroxyphenyl)Methyllidene]Amino}Ethyl I Methyl} Phenol-Copper ((li) Complex Nighat Afza, Itrat Anis, M. Aslam, A Hussain, M.Safdar, A.H. Chaudry, Lubna Iqbal, Mehreen Lateef, Qayyum, M. Niaz. and Tahir Rehman. International Journal of Current Pharmaceutical research, (2013) 83-85. | ||
| 92. | Antioxidant activity and structure activity relationship of some new Schiff bases derived from 2-Aminobenzophenone” Ghulam Fareed, Nighat Afza, Muhammad Ali Versiani, Nazia Fareed, Lubna Iqbal, Mehreen Lateef and Tahir Rehman, Medicinal Chemistry & Drug Discovery, (2013): 27-34. | ||
| 93. | Anthrarobin and its derivatives: evaluation of antibacterial and lipoxygenase inhibition activities” Mehreen Lateef, Samina Iqbal, Nizam uddin, Bina S. Siddiqui and Abid Azhar, Pakistan Journal of Biochemistry and Molecular Biology, (2013): 59-61. | ||
| 94. | Ophiamides A_B, New Potent Urease Inhibitory Sphingolipids from ophiogoglossum” Sadiqa Firdous, Nida Hassan Ansari, Itrat Fatima, Abdul Malik, Nighat Afza, Lubna Iqbal, Mehreen Lateef. Archives of pharmacal research, (2012): 1133-1137. | ||
| 95. | Bioactive Phenolic Amiides from Celtis Africana” Areej Mohammad, Al-Taweeel, Shagufta Perveen, Azza Muhammad El-Shafae, Ghada Ahmed Fawzy, Abdul Malik, Nighat Afza, Lubna Iqbal and Mehreen Lateef. Molecules, (2012); 2675-2682. | ||
| 96. | Biologically Active Bergenin Dervatives from Bergenia stracheyi” Farah Siddiq, Itrat Fatima, Abdul Malik, Nighat Afza, Lubna Iqbal, Mehreen Lateef, Saira Hameed and Sher Wali Khan. Chemistry & Biodiversity, (2012): 91-98. | ||
| 97. | Potent Antioxidant and Lipoxygenase Inhibitory Flavonone and Chalcone from Erythrina mildbraedii Harms (Fabaceae) of Cameroon” Muhammad Shaiq Ali, Muhammad Imran Ali, Ghafoor Ahmed, Nighat Afza, Mehreen Lateef, Lubna Iqbal, Alain F.K. Saffo and Zeeshan Ahmed. Zeitschrift für Naturforschung, (2012): 98-102. | ||
| 98. | Evaluation of Antioxidant and Urease Inhibition activities of roots glycyrrhiza glabra” Mehreen Lateef, Lubna Iqbal, Kauser Siddiqui, Nudrat Fatima, Nighat Afza, Zia ul Haq, Mansoor Ahmed. Pakistan Journal of Pharmaceutical Sciences, (2012): 99-102. | ||
| 99. | Estimation of Monosodium Glutamate by modified HPLC method in Various Pakistani Spices’ Formula” Mehreen Lateef, Kauser Siddiqui, Muhammad Saleem, Lubna Iqbal. Journal of Chemical Society of Pakistan, (2012): 39-42. | ||
| 100. | A one-pot synthesis, characterization and pharmacological investigations: Schiff bases” I. Anis, M. Aslam, N. Afza, A. Hussain, F. S. Ahmad, L. Iqbal, M. Lateef, M. T. Hussain, and T. H. Bokhari, International Journal of Pharmaceutical Chemistry, (2012): 73-77. | ||
| 101. | Bio reactive properties of citrus waste: An investigation of antioxidant and tyrosinase inhibitory activities” Musarrat Akhtar, Lubna Iqbal, Mehreen Lateef, Bushra Nawab, Muhammad Saleem and Nighat Afza, Pakistan Journal of Botany, (2011): 2881-2883. | ||
| 102. | Potent Antioxdant and Lipoxygenase Inhibitory flavanone and Chalcone from Erythrina mildbraedii (Fabaceae) of Cameroon” M.S Ali, G.Ahmad, M.I. Ali, L.Iqbal, N.Afza, M.Lateef, Alain..F,K. waffo, Z. Ahmad, Zeitschrift fuer Naturforshung, (2011) 98-102. | ||
| 103. | Sorbicins A and B, new urease and serine protease inhibitory triterpenes from Sorbus cashmiriana” Mehdi Hassan Kazmi, Itrat Fatima, Abdul Malik, Lubna Iqbal, Mehreen Latif and Nighat Afza, Journal of Asian Natural Products Research, (2011) 1081-1086. | ||
| 104. | Antixodant and urease inhibitory C-glycosylflavonoids from Celtis Africana” Shagufta Perveen, Azza Muhammad El-Shafae, Areej Al-Taweel, Ghada Ashmed Fawzy, Abdul Malik, Nighat Afza, Mehreen Latif and Lubna Iqbal, Journal of Asian Natural Products Research, (2011): 799-804. | ||
| 105. | Allo-Imperatorin: A Potent Urease Inhibitor from Fresh Unripe Fruits of Aegle marmelos (Rutaceae)” Muhammad Shaiq Ali, Ghafoor Ahmed, Muhammad Kashif Pervez, Mehreen Lateef, Nighat Afza and Lubna Iqbal, Journal of Chemical society of Pakistan, (2011): 960-964. | ||
| 106. | Relationship of leptin with BMD in postmeopausal osteoporosis” Lateef M, Baig M and Azhar A, Osteoporosis Internationa (2011): 23S. | ||
| 107. | Conferin, Potent antioxidant and Antiinflammatory isoflavone from Caragana Conferta” S. Naz, I Fatima, N. Riaz, N. Afza, A. Malik, M. Lateef and L. Iqbal, Journal of Enzyme Inhibition & Medicinal Chemistry, (2010): 440-444. | ||
| 108. | Estimation of serum osteocalcin and telopeptide-C in postmenopausal osteoporosis” Mehreen Lateef, Mukhtiar Baig, Abid Azhar, Osteoporosis International, (2010): 751-755. | ||
| 109. | Relationship of Age, BMI, Serum Calcium and estradiol with BMD in postmenopausal osteoporotic Females” Mukhtiar Baig, Mehreen Lateef, Abid Azhar, Journal of Bharia University, Medical & Dental College, (2010): 25-29. | ||
| 110. | Mutiniside, New Antioxidant Phenolic Glucoside from Abutlion muticum” S. Ali, S. Yasmeen, N. Afza, A. Malik, M. Lateef, N. Riaz, M. Ashraf, Journal of Asian Natrual Product Research, (2009): 457-464. | ||
| 111. | Lipoxygenase Inhibitory Tetraketones; Potential Remedial Source for inflammation and Asthma” S. Ali, G. M. Mharvi, N. Riaz, N. Afza, A. Malik, M. Lateef and L. Iqbal, West Indian Medical Journal, (2009): 93-95. | ||
| 112. | Asphorodin, Potent Lipoxygenase Inhibitory Triterpene Diglycoside from Asphodelus tenuifolius” S. Khan, S. Yasmeen, N. Riaz, N. Afza, A. Malik, M. Lateef and L. Iqbal, Journal of Asian Natrual Products Research, (2009): 945-950 | ||
| 113. | Structural determination of salsolins A and B, new antioxidant polyoxygenated triterpens from Salsola baryosma by 1D and 2D NMR spectroscopy, Zaher Ahmad, Sajid Mehmod, Itrat Fatima, Abdul Malik, Rehana Ifzal, Nighat Afza, Lubna Iqbal, Mehreen Lateef and Tanver Ahmad Nizami, Magnetic Resonance in Chemistry, (2008):94-98. | ||
| 114. | New butryl cholinesterase Inhibitory Steroid and Peroxy acid from Leucas Utricifolia, Itrat Fatima, Ijaz Ahmed, Itrat Anis, Abdul Malik, Nighat Afza, Lubna Iqbal, and Mehreen Lateef, Archieves of Pharmceutical Resonance, (2008): 999-1003. | ||
| 115. | Mild and efficient syntheses of lipoxygenase inhibiting and antioxidant tetraketones, Ghulam Murtaza Maharvi, Samar Ali, Naheed Riaz, Nighat Afza, Abdul Malik, M. Ashraf, Lubna Iqbal and Mehreen Lateef, Journal of Enzyme Inhibition and Medicinal Chemistry, (2008): 62-69. | ||
| 116. | Cotonoates A and B, new aromatic esters from Cotoneaster racemiflora, Shafiullah Khan, Shazia Yasmeen, Nighat Afza, Abdul Malik, Lubna Iqbal and Mehreen Lateef, Z. Naturforschung, (2008): 1219-1222. | ||
| 117. | Studies On Amylase Activity Of Pancreatin Obtained From Bovine Pancreas, Zaman Niazi, Kauser Siddiqui, Lubna Iqbal and Mehreen Lateef, Pakistan Journal of Scientific and Industrial Research, (2008): 242-244. | ||
| 118. | Determination of Radical Scavenging Activities and Reduction Capabilities of Tetraketones derived from 5, 5-dimethyl-1, 3 cyclohexanedione, Lubna Iqbal, Samar Ali, Mehreen Lateef, Abdul Wahab Zahid and Nighat Afza, Pakistan Journal of Biochemistry and Molecular Biology, (2006): 36-40. | ||
| 119. | Role of Coriandrum Sativum as antioxidant, Lubna Iqbal, Mehreen Lateef, Abdul Wahab Zahid, Nudrat Fatima, Nighat Afza, Pakistan Journal of Biochemistry and Molecular Biology, (2006): 95-98. | ||
| 120. | Antioxidant activities of tetraketones derived from 5,5 dimethylcycohexane-1,3- dione, L. Iqbal, M. Lateef, S. Ali, N. Riaz, G. M. Maharvi, M. Ashraf and N. Afza, Journal of Chemical Society of Pakistan, (2006): 51-54. | ||
| 121. | Leufolins A and B, potent Butyrylcholinesterase inhibiting Flavonoid Glucosides from Leucas urticifolia, Atia-tun-Noor, Itrat Fatima, Ijaz Ahmed, Abdul Malik, Nighat Afza, Lubna Iqbal, Mehreen Lateef, Sher Bahadur Khan, Molecules, (2006): 1447-1454. | ||
| 122. | Correlation between circulating leptin and gonadotrophins during the menstrual cycle in infertile females, Mukhtiar Baig, Abid Azhar, Mehreen Lateef and Perveen Zaidi, Pakistan Journal of Biochemistry & Molecular Biology, (2006):115-119. | ||
| 123. | Role of Serum Osteocalcin in Diagnosis of Postmenopausal Osteoporosis, Mehreen Lateef,Mukhtiar Baig & Abid Azhar, Pakistan Journal of Biochemistry & Molecular Biology, 38: 56-60. | ||
| 124. | Depression of Plasma Testosterone Level by Heroin Addiction and its Restortion by the Withdrawl of the Drug, Abid Azhar, Arif Siddiqui, Nosheen Afzal, Mukhtiar Baig and Mehreen Lateef, Pakistan Journal of Biochemistry & Molecular Biology, (2003) 73-78. | ||
| RESEARCH | |||
| 1st May 2014- 1st May 2015 | Establishment of Molecular Biology Lab and MultiDisciplinary Research Lab (1.7 Million) Bahria University | ||
| 1st Jan 2017- 31 Dec 2018 | Establishment of Histopathology and Pharmacology Lab (1. Million) Bahria University | ||
| 1st Jan 2019 -30 June 2019 | Soil properties of shrimp aqua culture farm (0.4 Million) HEC | ||
| 1st Jan 2020 -30 June 2020 | Association of Fractline with Inflammatory Markers in Diabetes Mellitus (0.5 Million) MLTAP | ||
| 2-Nov-2020-2-Dec 2021 | Evaluation of bone loss in male smokers by genetic analysis of oxidative (0.98 Million) SRGP-HEC and biochemical bone markers | ||
| 1st Dec-2021- 1st Dec 2024 | Esterase inhibitors as possible therapeutic agent in Alzheimer’s disease: An approach to perform genetic analysis and improve mental health related issues in society | ||
| 1st jan-2021-31-Dec 2022 | Development of memory boost nutraceutical from indigenous marine sources (0.7 Million) BU | ||
| 1st jan-2021-31-Dec 2022 | Marine bioprospecting of novel bioactive compounds from medicinally (0.6 Million) BU important unexplored species for drug discovery | ||
| 1st jan-2021-31-Dec 2022 | Effect of naturally isolated bioactive compounds as antioxidant (antirust) (1.2 Million) BU and dispersive agent for coating material of ships: a green approach to prevent marine biofouling | ||
| Other Research or Creative Accomplishments | Patents 1. A Process for the Preparation of Lactase free Milk supplement for Lactose Intolerant Population” Mehreen Lateef, M. Saleem Qazi, Lubna Iqbal, Nighat Afza SI no 1205/20082. A Process for the preparation of an analgesic cream for joints and arthritis pain, Kauser Siddiqui, Kanwal Abbasi, Mehreen Lateef, Muhammad Saleem, Lubna Iqbal, Muhammad Riaz, Kaniz Fizza Azher, SI no: 141669.3. A Process for the Preparation of Topical Analgesic Cream for Traumatic Pain, Kauser Siddiqui, Samina Iqbal, Mehreen Lateef, Kanwal Abbasi, Muhammad Saleem, Saeeda Bano, Lubna Iqbal. SI no: 605/20134. Development Of Antiviral immune energizer: Unique Formulation to treat and manage COVID-19 Mehreen Lateef, Shizma Juneejo, Ambreen Usmani , Kauser Sidduiqui (Patent Filed: Application no: 732/20215. Development of novel memory boost nutraceutical formulation with neuroprotective functions”M Mehreen Lateef, Laraib Liaquat, Shizma Juneejo, Kauser Sidduiqui Patent application no 314/2026. Biobased novel anticorrosive composition for ship steel coating” (ii) that we (Dr. Mehreen Lateef, Ms. Hiba Saleem, Dr. Laraib Liaquat, Dr. Madiha Kanwal Patent Application no 417/2023 |
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| RESEARCH PROJECTS COMPLETED |
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| Research Projects Completed | 1. Evaluation of serum vitamin D levels in Pre and Post-Menopausal Females of Karachi, Pakistan 2. Association of Iron-Deficiency Anemia and BMI for predicting health status among young population/ university students 3. Anti-platelet activity of some potential therapeutic phytopharmaceuticals for cardiovascular diseases 4. Safety and tolerability of sacubitril/ valsartanin heart failure patient with reduced ejection fraction 5. Smart phototherapeutic device with analgesic effect 6. Evaluation of tumor suppressor protein level in oral squamous cell carcinoma 7. Role of behavioural alteration and urinary parameters in the earlier diagnosis of autism spectrum disorders 8. Analysis of cell signalling pathway protein level in oral squamous cell carcinoma 9. Effect of oxidative stress in the occurrence and progression of stroke 10. Role of interleukin-23 as diagnostic biomarker in rheumatoid arthritis 11. Increased serum Fractalkine CX3CL1 linked to type 2 Diabetes Mellitus (T2DM) pathogenesis 12. Estimation of Bone markers in postmenopausal osteoporosis 13. Isolation, Purification and Characterization of β-galactosidase from Microbial Source. 14. Biological activities of compounds isolated from native wild flora of Karachi 15. Enzyme Inhibition Activities of Naturally Isolated and Synthetic Compounds 16. Human Serum Analysis for Antioxidant Parameters (Glutathione, superoxide dismutase, total antioxidant activity, endothelin, C reactive protein) by Kit methods in Cardiac patients 17. Effect of Haptoglobin gene polymorphism on Heat Shock Protein and other Markers in type II diabetic patients with and without nephropathy. 18. Bioequivalence and Bioavailability of Isoquinonoe group of drugs 19. Shelf life of Mutton, Beef & Camel Meat 20. Stability Studies of Ferromate Tablets (210 mg) LDPE jar at intermediate conditions 21. ORS Liquid Product Stability studies 22. Preparation of value added Enzyme based products for gastrointestinal disorders. 23. Evaluation of medicinal Plants including , Litchi chinensis, Achras sapota L., Rubus niveus, Alstonia scholaris, Annona squamosa and Eriobotrya japonica, in addition the study and analysis of their chemical constitutes 24. Biological activities of synthethic anthraquinones & Carbamate Derivatives 25. Stability Studies of lactase for lactose Intolerance 26. Evaluation of Biochemical Signaling Pathways involved in Platelet Aggregation inhibition pathway of new anthrarobin derivatives. 27. Method Devlopment and Validation of MonosodiumGlutamate in National Spices 28. Antiplatelet Studies of various synthetic compounds involving aggregation and secretion in human platelet rich plasma and washed platelets against various inducers. 29. Molecular Analyses of Human Human P2Y12 (Agonist-bound Structure receptor) function reducing gene mutation/ polymorphism will be done by PCR-RFLP and direct DNA sequencing. 30. Development of various assays of Enzyme inhibition studies against new synthetic and isolated compounds or including antioxidant, urease, tyrosinase, cholinesterase, chymotrypsin and lipoxygenase inhibition. 31. Evaluation of serum vitamin D levels in Pre and Post-Menopausal Females of Karachi, Pakistan 32. Association of Iron-Deficiency Anemia and BMI for predicting health status among young population/ university students 33. Anti-platelet activity of some potential therapeutic phytopharmaceuticals for cardiovascular diseases 34. Safety and tolerability of sacubitril/ valsartanin heart failure patient with reduced ejection fraction 35. Smart phototherapeutic device with analgesic effect 36. Evaluation of tumor suppressor protein level in oral squamous cell carcinoma 37. Role of behavioural alteration and urinary parameters in the earlier diagnosis of autism spectrum disorders 38. Analysis of cell signalling pathway protein level in oral squamous cell carcinoma 39. Effect of oxidative stress in the occurrence and progression of stroke 40. Role of interleukin-23 as diagnostic biomarker in rheumatoid arthritis 41. Increased serum Fractalkine CX3CL1 linked to type 2 Diabetes Mellitus (T2DM) pathogenesis |
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| RESEARCH GRANTS | |||
| Date | Title | Donar | Amount |
| 1st Dec-2021- 1st Dec 2024 | Esterase inhibitors as possible therapeutic agent in Alzheimer’s disease: An approach to perform genetic analysis and improve mental health related issues in society | HEC-NRPU | 10.058 Million |
| 1st jan-2021-31-Dec 2022 | Development of memory boost neutraceutical from indigenous marine sources | Bahria University | 0.7 Million |
| 1st jan-2021-31-Dec 2022 | Marine bioprospecting of novel bioactive compounds from medicinally important unexplored species for drug discovery | Bahria University | 0.6 Million |
| 1st jan-2021-31-Dec 2022 | Effect of naturally isolated bioactive compounds as antioxidant (antirust) and dispersive agent for coating material of ships: a green approach to prevent marine biofouling | Bahria University | 1.2 Million |
| 1st Jan 2020 -30 June 2021 | Association of Fractline with Inflammatory Markers in Diabetes Mellitus | Medical Lab Technologist Association of Pakistan | 0.5 Million |
| Evaluation of bone loss in male smokers by genetic analysis of oxidative and bio chemical bone markers | SRGP-HEC | 1.0 Million | |
| 1st Jan 2019- 30 June 2019 | Soil properties of shrimp aqua culture farm | NRPU-HEC | 0.4 Million |
| 1st Jan 2017-
31st Dec 2018 |
Establishment of Histopathology and Pharmacology Lab | Bahria University | 1.0 Million |
| 1st May 2014- 1st May 2015 | Establishment of Molecular Biology Lab and Multidisciplinary Research Lab | Bahria University | 1.7 Million |
| Supervision/ Co supervision | HEC Approved Supervisor | |||
| Years | Degree | Name | Institute |
| 2022 Onwards | MPhil | Allah Baksh | Department of Biochemistry, BU |
| 2022 Onwards | MPhil | Fiaza Sohail | Department of Biochemistry, BU |
| 2022 Onwards | MPhil | Madiha Shakeel | Department of Biochemistry, BU |
| 2023 | BS | Maheen Waqar | BUCAHS |
| 2023 | BS | Kaniat Ahsan | BUCAHS |
| 2021-22 | PhD | Mahm Ghouri | KIBGE, University of Karachi |
| 2021 | BS | Aimon Khan | Department of MLT, BU |
| 2021 | BS | Aqsa Maqsood | Department of MLT, BU |
| 2021 | BS | Saba Ahmed | Department of MLT, BU |
| 2017 | MS | Shehroz Khan | Department of Zoology, KU |
| 2017-18 | MS | Maria Habib | Department of Zoology, KU |
| 2015-18 | PhD | M. Amin | Department of Zoology, KU |
| 2018-19 | MPhil | Humam Ahmed | Department of Chemistry, KU |